Anime have had a chance to get lost in all kinds of magical worlds. In these worlds, they meet with terrifying, hilarious, and some of the smartest isekai anime characters. Even though these anime are story-focused, many of them have brilliantly crafted characters who became some of the most iconic heroes and villains of anime history.

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The best isekai anime of all time feature epic battles between good and evil, as well as twisty stories and surprising plot twists. Most of these adrenaline-boosting adventures were thanks to devious villains who used their power and exceptional intelligence for evil. Isekai anime lovers can get lost in stories set in modern, fantasy, and historical worlds that are filled with dark secrets and epic adventures.

7 Tanya Degurechaff - Saga Of Tanya The Evil

Tanya Degurechaff in Saga Of Tanya The Evil

Saga Of Tanya The Evil is one of the darkest and most unique isekai anime series with a truly ruthless and terrifying main character. Its lead is a seemingly fragile small girl, Tanya Degurechaff, who turns out to be one of the most cunning and ruthless murderers of all time. She was responsible for the death of over a hundred humans since she started her journey in the War College.

The anime takes place in an alternate timeline set during WWI and follows the story of a man who was reincarnated as Tanya after making a bet with an all-powerful creature called Being X. The two get into a battle of wits that leads to Tanya becoming one of the most powerful and ruthless soldiers, who helps his nation become one of the most powerful ones that ever existed.

6 Naraku - Inuyasha

Naraku in Inuyasha

Even though Inuyasha was mainly a love story, it also had a great and adventures-filled story and one of the most terrifying isekai anime villains of all time. Naraku was this fantasy anime's darkest character. He loved torturing not only Inuyasha, but everyone else around him too.

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This fun and emotional show also had some of the most powerful demon lords in anime who often battled against each other. However, none of them found as much pleasure in others suffering as Naraku. He only cared about increasing his own power and killing or tormenting those who stand in his way.

5 Malty S. Melromarc - The Rising of the Shield Hero

Malty S. Melromarc in The Rising of the Shield Hero

Malty S. Melromarc is one of the most hated and terrifying isekai anime characters of all time. The Rising of the Shield Hero's sociopathic villain is not above stealing, lying, or murdering anyone who stands in her way. Thanks to her vile ways, she quickly became Naofumi's most odious enemy.

Malty was the first Princess of the Melromarc Kingdom, who used her magic knowledge and devious mind to get what she wants. Even though there are plenty of powerful vassal weapons in the series, Malty didn't really show her skills in combat and preferred to use trickery instead of brute force.

4 Wang - Darwin's Game

Wang in Darwin's Game

Darwin's Game is one of the newest dark psychological anime series, with plenty of terrifying characters. However, Wang easily stands out from them all. Wang is one of the most terrifying anime characters of all time. He enjoys brutally murdering people as well as torturing them both physically and emotionally.

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Even though he is a sadistic psychopath, he is still one of the most intelligent characters, which just makes him even more horrifying. Despite the fact that he didn't want to join the game, he soon learns to love it when he realized he can torture and kill people and do pretty much anything he wished thanks to his cunning mind and his powerful sigil Beelzebub.

3 Akihiko Kayaba - Sword Art Online

Akihiko Kayaba in Sword Art Online

Akihiko Kayaba is Sword Art Online's creator and game master who trapped all players in the game. He was responsible for thousands of children and adult gamers' deaths, and he never showed remorse of any kind.

SAO was a visually beautiful anime with awesome world-building and mighty characters. Kayaba's was the most powerful of them all. Even after his horrible acts, he still showed respect toward skilled players. His character in the game, Heathcliff, was undefeatable, and he murdered plenty of villains and virtuous players who tried to achieve the impossible and beat him in his own game.

2 Ainz Ooal Gown - Overlord

Ainz Ooal Gown in Overlord

Ainz Ooal Gown is one of the creepiest looking and scariest Overlord-type characters in Overlord. He is the Sorcerer Kingdom's all-powerful King who got completely obsessed with power and increasing his own abilities. He uses his exceptional capabilities to murder and brainwash people, and he does so with intense pleasure.

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Since he is the most powerful and dangerous magic caster in his world, he is feared by many, especially by those who know he is also a highly intelligent villain who always plans his steps in detail. He is a fearful and interesting villain in Overlord's gorgeously designed and adventure-filled world.

1 Yubaba - Spirited Away

Yubaba in Spirited Away

Yubaba is easily one of the most well-known and creepiest isekai anime characters, thanks to Spirited Away's international success. She was the powerful and often scary owner of the anime's iconic Bathhouse where spirits came to unwind.

Yubaba served as a villain in the movie, since she represented evil while her twin Zeniba represented good. However, was also honest when it came to business. She is also a powerful magic user who can manipulate reality itself, and can transform any living thing or object into anything else she wished.

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