The Binding of Isaac: Repentance

The Binding of Isaac: Rebirth has received its final DLC expansion with The Binding of Isaac: Repentance. This expansion adds two new playable characters, over 150 new items, over 100 new enemies, and over 25 new bosses.

The new bosses for The Binding of Isaac are spread throughout existing floors as well as the new areas included with the DLC. Some of these bosses are original to this expansion while others actually originated from the fan-made Antibirth expansion.

Counting all of them, there is a total of 31 new bosses included with The Binding of Isaac: Repentance. Each of them will provide returning players with plenty of new challenges to face and new projectile patterns to learn in the heat of the moment.

Old Areas

While the new environments have their own unique bosses added, many of the pre-existing locations have gotten their own new bosses that players can enjoy before the new areas are unlocked. These bosses are:

Baby Plum

Areas found: The Basement, Cellar, and Burning Basement
Base HP: 234

Bumbino

Areas found: The Caves
Base HP: 385

Great Gideon

Areas found: The Caves, the Catacombs, and Flooded Caves
Base HP: N/A (Wave-based fight similar to Greed Mode)

Tuff Twins

Areas found: The Caves, the Catacombs, and Flooded Caves
Base HP: 35 (Tough exterior and must be exposed via bombs)

The Shell

Areas found: The Caves, the Catacombs, and Flooded Caves
Base HP: 35 (Tough exterior and must be exposed via bombs)

Singe

Areas found: The Caves, the Catacombs, and Flooded Caves
Base HP: 444

Reap Creep

Areas found: The Caves and the Depths
Base HP: 690

The Pile

Areas found: The Caves, the Catacombs, Flooded Caves, and Necropolis
Base HP: 580

Downpour/Dross

Two of the new floors added for this expansion are Downpour and Dross. Downpour can be unlocked after players defeat Hush at least three times with Dross being unlocked after players beat all the bosses in Downpour.

These two areas share some bosses with some only appearing in one or the other. The bosses for these areas are.

The Rainmaker

Areas found: Only in Downpour
Base HP: 200

Lil Blub

Areas found: In both Downpour and Dross
Base HP: 130

Min Min

Areas found: Only in Downpour
Base HP: 280

Wormwood

Areas found: In both Downpour and Dross
Base HP: 200

Clog

Areas found: Only in Dross
Base HP: 420

Colostomia

Areas found: Only in Dross
Base HP: 380

Turdlet

Areas found: Only in Dross
Base HP: 190

Mausoleum and Gehenna

Two new alternatives for the Depths that have been added are the Mausoleum and Gehenna. These new areas have their own new bosses that are exclusive to them and they are:

The Siren

Areas found: Only in the Mausoleum
Base HP: 666

The Heretic

Areas found: Only in the Mausoleum
Base HP: 789

The Visage

Areas found: Only in Gehenna
Base HP: 620

The Horny Boys

Areas found: Only in Gehenna
Base HP: 707

Corpse

Corpse is a new alternate area for the Womb, Utero, and Scarred Womb levels that players can enter. This area has its own set of bosses that can be challenged including a new alternative for Mom's Heart and It Lives. These bosses are:

Rotgut

Areas found: Corpse
Base HP: 1800

Chimera

Areas found: Corpse
Base HP: 1050

The Scourge

Areas found: Corpse
Base HP: 950

Mother

Areas found: Corpse
Base HP: 4222

WARNING: MAJOR SPOILERS BELOW.

Home

The true final area of The Binding of Isaac is Home, where the last bosses of the game lie. Defeating them will lead players to the game's true ending which won't be an easy job. These bosses are:

Dogma